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History:
Disulfiram (Antabuse) was invented by Medicinalco (well-known Danish drug corporation) in 1948. Scientists Jens Hald, Erik Jacobsen and Keneth Ferguson discover the substance was intended to provide a remedy for parasitic infestations. But researchers testing the substance on themselves reported severe symptoms after alcohol consumption.
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Antabuse (Disulfiram) is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Brand names of this drug in different countries are Antabuse, Antabus and Disulfiram. It also being studied as a treatment for narcotic dependence, as it prevents the breakdown of dopamine (a neurotransmitter whose release is stimulated by cocaine); the excess dopamine results in increased anxiety, higher blood pressure, restlessness and other unpleasant symptoms. Several studies have reported that it has anti-protozoal activity as well. Also announced research for possible disulfiram use in cancer therapy.Generic Antabuse interferes with the metabolism of alcohol resulting in unpleasant effects when alcohol is consumed. This pill to cure alcoholism may also be used for purposes other than those listed in this medication guide.
Alcoholism Treatment, Cure Alcoholism
Disulfiram (Antabuse) was the first medicine approved for the treatment of alcohol abuse and alcohol dependence. Cheap Antabuse is the first drug approved for the alcohol abuse treatment. It used also to treat alcohol dependence by the U.S. Food and Drug Administration.It is prescribed to help people who want to quit drinking by causing a negative reaction if the person drinks while they are taking this product.
Do not drink alcohol while taking generic Antabuse. Side effects in this case: Thirst, Flushing, chest pain, fast heartbeats, nausea, vertigo, and low blood pressure. Each tablet for oral administration contains 250 mg or 500 mg disulfiram, USP. Tablets also contain colloidal silicon dioxide, anhydrous lactose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, and stearic acid.
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Reactions may occur from drinking alcohol for several weeks after you have stopped taking this drug. Do not take generic Disulfiram for at least 12 hours after drinking alcohol. Patients who are receiving or have recently received metronidazole, paraldehyde, alcohol, or alcohol-containing preparations, e.g., cough syrups, tonics and the like, should not be given disulfiram. Be aware of the alcohol content of other common products such as cough and cold medicines, mouth washes, tonics, sauces, vinegars, and other food products. Antabuse Disulfiram is contraindicated in the presence of severe myocardial disease or coronary occlusion, psychoses, and hypersensitivity to disulfiram or to other thiuram derivatives used in pesticides and rubber vulcanization.